Why Naltrexone?

Why Naltrexone?

Naltrexone is an FDA approved prescription medicine that not only reduces or eliminates any desire for alcohol and drugs, but effectively blocks their effects as well. Can be very effective for: alcohol, heroin and all opioid drugs including Vicodin®, Oxycodone, Hydrocodone and many prescription pain medications.

It has shown to help significantly improve the success rate for alcohol and addiction recovery. In 1984, the FDA approved an oral pill of this drug for chronic opioid addiction, and in 1993 for alcohol addiction. This form of treatment has not been very effective however, because patients need to take the drug on a daily basis in order for it to block the opioid effects. In fact, oral Naltrexone has a 90% failure rate. Patients who have not yet developed the essential coping skills are at an extreme high risk for relapse. Relapse can easily occur because they can stop taking the medication (or forget) and turn to drugs whenever circumstances or events trigger a stress response that the addict feels they can’t handle.


Naltrexone is also available in a monthly injection as a prescription drug called Vivitrol®. The monthly injection eliminates the problem of daily dosing, but can be very painful with the large needle and intramuscular injection, can cause an abscess, requires frequent doctor visits and has a high failure rate as well. Add in the monthly ups and downs of the treatment, and well… This is a better option than the oral dose, but the monthly expense, scheduling, significant discomfort (large needle) during the intramuscular shot, as well as the short duration of effectiveness make it less than ideal as a treatment option, and with a high failure rate similar to that of oral dosing.


A more recent option (and the one with the greatest potential for success) for delivering Naltrexone is an extended release pellet placed under the skin. This option offers the best duration of benefits with a lower cost per month for the recovering alcoholic or addict. While Naltrexone is being slowly released into the body, the sustained level of medication blocks the effects of alcohol and opioids so it is virtually impossible to relapse, and it allows a mind to be free and clear for recovery without the ravaging obsessions to use and drink. Just as importantly, it eliminates the need to take pills or injections, thus removing the crucial ‘compliance’ factor. What many find extremely beneficial, too is the constant 24/7 delivery of the medicine eliminates the highs and lows (a major cause of relapse) from any other method of administration. Eliminating the variables for relapse is of crucial importance, hence the pellet implant’s effectiveness.

Are Naltrexone Implants Safe?

Based on our experience, yes. FDA-approved pharmacists manufacture the implant containing FDA-approved Naltrexone for each individual patient in FDA-approved facilities while maintaining the highest pharmaceutical quality standards. The Naltrexone 100% biodegradable pellets themselves have not yet been cleared by the FDA. but Naltrexone itself had been FDA-approved for over 30 years. Initial studies suggested that, in rare cases, it could cause additional liver problems in patients with acute liver disease such as hepatitis, but in practice it has been extremely well tolerated by most patients.

Patients receiving the pellets obviously can expect slight bruising and discomfort for a short time after the simple outpatient procedure. There is also a very small risk of post procedure infection but this has not occurred in any of our patients. If a Naltrexone program is started before the patient has significantly detoxed from the opioids, the pellet will cause severe opioid withdrawal symptoms. Worth noting, is if a patient on naltrexone therapy were in an accident where narcotic medicines are normally used for pain relief, the narcotics would have no effect.

Should the patient be injured after the procedure and require analgesia (pain medications), they must inform the doctor that he is on naltrexone maintenance therapy so an alternative medication may be prescribed. Because the patient may be involved in an accident or some other occurrence that renders him unable to inform the doctor that he is on the medication, it is recommended that they wear a Medic-Alert tag which advises the doctor that the patient is receiving naltrexone maintenance therapy.

If patients try to override the blocking effects of naltrexone and abuse narcotics they have a very unpredictable and dangerous risk of a fatal overdose. Patients also need to be especially careful after the implant wears off because they no longer have a tolerance for the drug. The same amount of drug previously used after a period of abstinence can be fatal.

How Does Naltrexone compare with Opioid Maintenance Therapy (OMT) Drugs such as Methadone, Suboxone®, and Subutex®?

Unlike these drugs, naltrexone does not have an ‘opioid effect’ or produce any sort of high; it is non-narcotic, non-addictive and non-mood altering. Because of this fact, naltrexone is allowed in most treatment recovery programs and in sober living homes. In addition, once a person is on naltrexone, they cannot get high from opioid use and they can stop without any withdrawal symptoms. Although OMT drugs can be useful in short-term detox programs, they should not be continued for an extended period. This reduces the potential medical addiction to these prescription drugs that become just as difficult, if not more, to quit as heroin or pain medications. Remember, too, these medications typically have major withdrawal symptoms of their own, as well as requiring a full detox program.

Is a Naltrexone Implant a Cure to Opioid or Heroin Addiction?

In a word: no. We believe strongly that naltrexone pellet therapy by itself is not a cure, but during the period of its opioid blocking effects it virtually eliminates the possibility of relapse. This is the key for many addicts that want to recover but believe it is impossible when they are dealing with the daily cravings. Freedom from the cravings, and knowing there is no reward of getting high, allows the recovering addict who is 100% committed to recovery to put all of their mental focus on professional, expert therapy. Further, studies have shown that the best indicator of long-term recovery is continued participation in a peer recovery program such as a 12 step, SMART or CELEBRATE. Most addicts have not developed the life skills and behaviors required for lifelong sobriety. This is the real work in addiction recovery and one that cannot be ignored or assumed to take care of itself while enjoying the freedom from cravings. Naltrexone therapy without the appropriate therapy and Peer Support program is almost always unsuccessful.

Naltrexone and Success with Alcoholism Treatment

The ultimate goal of recovery from alcoholism is abstinence and learning how to live a happy, prosperous and fulfilling life without drinking. There are also a number of medicines that can assist in achieving and maintaining abstinence. Naltrexone is probably the most powerful of these medicines. Naltrexone is a drug that attaches to the opiate receptors in the brain and blocks them. Part of the pleasurable effect from alcohol happens through these opiate receptors. When these receptors are blocked, people get fewer cravings for alcohol and less pleasure if they do drink any alcohol. It becomes much easier for them to stay abstinent and continue with their recovery program.

How Long Should I Stay on Naltrexone Therapy?

We believe strongly that patients should be on naltrexone pellet therapy for a minimum of 6 to 12 months for the best chances of a lasting recovery. This essentially prevents them from relapsing back to alcohol or narcotic use and gives them at least a year to start making changes in their lives and working in a support group. Patients that decide they want to continue with the naltrexone therapy can receive additional pellets or transition to daily oral naltrexone medication. There are no long-term complications or side effects from the low dose naltrexone therapy. In fact, low dose naltrexone therapy has been found to actually strengthen and improve the immune system, and has been used successfully in illnesses such as cancer, arthritis, chronic fatigue, fibromyalgia, and MS.

Am I a candidate for a Naltrexone Implant Program?

Naltrexone would be appropriate for any alcoholic or opiate addict who desperately wants to stop but has never managed to stay sober for a long period. The term we use to best describe this person is that they are in a “state of readiness”. A person may say they are ready to recover, however this will only be confirmed through their actions that will be obvious to their peer recovery group, their therapist, their family and friends, etc. The recovering alcoholic/addict will consistently make life-affirming changes that demonstrate self-reliance and emotional maturity. Naltrexone is very helpful for those that are ready but know that relying on will power or counseling alone will not work for them. Naltrexone is NOT a narcotic or mood-altering drug and is therefore not objectionable to most recovery programs or sober living homes that require abstinence. Along with our 1:1 Counseling and Peer Recovery Support Specialists network, participation in a 12-step recovery program or similar is a primary, crucial form of follow-up care. We believe there is no substitute for the therapeutic value of one alcoholic or addict helping another to sobriety.

What’s the process of evaluation and treatment with Naltrexone pellet therapy?

A person needs to be free from alcohol, opiates or heroin for a minimum of one week before receiving a naltrexone pellet. Those on Methadone, Suboxone® or Subutex® should be off their prescription for at least 10-14 days because these drugs take longer to clear from the body. Even if no opioids have been taken for the recommended time, there may be some mild to moderate withdrawals due to the chronic imbalance in the essential brain neurotransmitters. We require a simple blood test, a basic screening and exam to decrease the risks and increase the success of Naltrexone therapy. We will also perform a urine drug screen immediately prior to the pellet insertion. The procedure is simple and takes just a few minutes to perform. The doctor will numb the area and then make a small incision and place one pellet under the skin. The incision is closed with a few stitches and the patient is sent home or could even go back to work if they desire.

It is recommended that patients wear a Medic-Alert tag (bracelet or necklace) that would inform a treating physician that the patient is on naltrexone maintenance therapy in the event that the patient is not able to communicate this information. The physician would obviously need to prescribe a non-opiate medication if pain relief was required. There are very few side effects from naltrexone and none of them are serious. It is difficult to determine whether the symptoms that are sometimes experienced are due to the naltrexone or the last remnants of the withdrawal syndrome. The withdrawal symptoms do not occur with every patient, especially if the addict has not used drugs for an extended period. Even if the patient experiences some withdrawal symptoms, they are generally mild compared to acute withdrawals experienced during drug detox, and cease within a week or so.

Are follow up appointments necessary?

​Approximately one week after the procedure, patients may return to the clinic to have the stitches removed. Our single pellet lasts approximately 6 months, the duration of effectiveness varies with each individual.

Why do we use Naltrexone?

  • AFFORDABLE Naltrexone file

What role does Naltrexone play in the program? The good doctor explains

What exactly is Naltrexone?

Naltrexone is an FDA approved medicine that serves as an ‘opioid receptor antagonist’, meaning Naltrexone blocks alcohol and opiates from activating the pleasure centers of the brain, and thus used to treat the dependence on them. Naltrexone blocks certain receptors in the part of the brain that trigger dopamine release and reinforces the vicious and compulsive addiction feedback loop. When these areas of the brain are blocked, the craving for alcohol is either eliminated entirely or at the bare minimum, significantly reduced. Then it naturally follows that the likelihood of drinking is either eliminated entirely or significantly reduced. And if alcohol is consumed, the pleasure is basically non-existent and any potential relapse is largely neutralized. It has proved highly effective in thousands of recoveries around the globe and for decades. Many individuals state that Naltrexone alone was responsible for saving their life. There is a large and growing body of evidence to help in your research to help determine if it is right for you. More:

What form of Naltrexone do you use?

The innovative, non-addictive Naltrexone 6 month mini-pellet implant manufactured by BioCorRx (why BioCorRx?).

“In most cases, our science-based recovery program utilizes the FDA-approved Naltrexone drug, which removes the euphoria, reinforcing effects, and physical cravings associated with alcohol consumption and opiate use. This quick outpatient procedure immediately begins to reduce the cravings for alcohol and opiates. The Naltrexone micro-pellet slowly releases the anti-craving formula into the body for up to 6 months or longer, in most patients, depending on individual characteristics and metabolism. Once the physical cravings for the abused substance is suppressed, patients are able to focus on their mental, emotional, and spiritual healing in order to successfully achieve a safe and sober lifestyle. This minimally-invasive outpatient procedure is performed by a board certified and trained surgeon in his surgical suite (requiring only local anesthetic and an approximate 1/2″ incision) and takes 15 to 20 minutes. Specifically formulated and biodegradable, the implant is inserted just beneath the skin in the lower abdominal area. More importantly, within hours of receiving the Naltrexone implant, many patients report feeling complete freedom from cravings. Most individuals are able to return to work the following day. Only the people with whom you wish to share know that you are enrolled in a rehab program.”

Check out the procedure:

Naltrexone works. Don’t take our word for it, there are decades of research from around the globe confirming its effectiveness as an anti-craving medication, and when combined with a comprehensive treatment program such as the one we offer, it can be one of the most powerful tools for recovery available anywhere in the world. Please visit our Research and Testimonial section for a start.

Your Brain & Naltrexone Get In Touch

Naltrexone Benefits

Naltrexone Benefits Overview

​Naltrexone has been used for quite some time in a variety of formulations in recovering addicts and has been proven to be quite effective especially in heavy drinkers: helps to substantially decrease the use of and hopefully eliminate the intake of alcohol.

The Naltrexone implant falls under the opioid antagonist family. Drugs like oxycontin and heroin contain opioids and as a norm for these drugs usually interact with the human body through opioid receptors. Naltrexone being an opioid antagonist usually works by blocking these opioid receptors and in doing so prevents the body from being affected by opioids from drugs.

Why are Naltrexone implants the best to treat opiate based addictions?

Naltrexone has the advantage of being time-tested and non-addictive in nature and as such, eliminates the craving for drugs giving an individual the opportunity to focus on the recover process. The Naltrexone implant is usually in form of a small non-narcotic pellet which as a norm is usually inserted under the skin near the lower abdomen: the medicine gets released into the body slowly over time. As a norm, local anesthesia is administered before the procedure is performed . The procedure usually takes a very short time and a patient is released soon after.

What benefits does Naltrexone Implant have over oral tablets?

When compared to oral tablets, Naltrexone implants are considered as being one of the best. For starters, Naltrexone implants have a significantly higher success rate when compared to oral tablets. The reason behind this is that, the Naltrexone implant is placed within an individual’s body and gets released into the body over time. As a result, an individual cannot skip, deliberate avoid or forget to take the medication: the primary reason tablets have low success rates with recovery. Sobriety with oral Naltrexone has demonstrated only a 10% success rate.

Does Naltrexone have side effects?

Some of the side effects that can be experienced on the site of implantation include:

  • Irritation of the skin
  • Inflammation at the site
  • Infection

When on Naltrexone use; some individuals might resort to take an extremely high dose of drugs so as to get a high. Even though the Naltrexone prevents the body from absorbing these drugs, an extremely high dose of drugs can be potentially lethal.
When the Naltrexone implant therapy ends, an individual’s body has been basically reset to its initial state and as a result, what was presumed to be a normal dose of the drug prior to the therapy can be a fatal dose if taken after this therapy.

How long is the Naltrexone therapy?

The Naltrexone implants/therapy can take anywhere from 2 to 12 months. However, it’s important to note that every patient is unique and as a norm, the rate of absorption of the drug varies on a case to case basis with some individuals absorbing the drugs faster than others.

Your Brain and Naltrexone

Alcohol & Opiate Addiction Your Brain and Naltrexone

What You Need to Know:

The Purpose of Naltrexone Treatment: To greatly reduce and eliminate the debilitating symptoms of cravings and withdrawal, enabling the patient to engage in therapy, counseling and support, so they can implement positive long-term changes in their lives which develop into the new healthy patterns of behavior necessary to achieve sustained addiction remission.

Addiction: a chronic disease

Addiction is classified as a disease because it negatively alters the biology of the brain from an otherwise healthy state. It’s considered a chronic disease because the changes are long-lasting. – The Essence of Addiction

Naltrexone is only a small part of the treatment and by itself would only serve to temporarily suppress symptoms of addiction which would likely reemerge upon cessation of the medication. Recovery is the process of reversing and/or coping with the abnormal brain adaptations responsible for the disruptive addictive behaviors. Medication merely helps facilitate this effort by suppressing symptoms of addiction.

The uncontrollable compulsive behaviors of addiction are the product of changes to the brain caused by chronic use and abuse of alcohol and opioids. Just as it took time for these changes to develop it takes time to reverse – to the extent they can be reversed. Some changes may be irreversible and for those changes, coping strategies need to be learned in order to deal with them successfully.

In broad terms, addiction is the manifestation of abnormal brain adaptations. These biological changes to the brain have an influence on behavior in unhealthy ways. The changes are responsible for the cravings associated with addiction. Humans, and animals, are innately programmed to crave and repeat activities determined to be necessary for survival and propagation of the species. Some natural examples are sex, food, exercise, and accomplishment. But the repeated artificial stimulation of the brain’s reward system with drugs and alcohol creates a memory and association which prompts repetition of destructive behavior via cravings.

In other words, the part of the brain responsible for survival is in effect hijacked and tricked into believing opioids are necessary for survival. And just as hunger and thirst prompt eating and drinking, the strong cravings prompt the person to repeat the behavior. It’s the strong cravings (created by your addiction) that are responsible for the uncontrollable compulsive behavior common to all addictions. It’s important to understand that the psychological experience of cravings is rooted in abnormally altered brain biology.

Successful addiction treatment consists of reversing, to the extent possible, the destructive brain adaptations. This is accomplished with a deliberate reconditioning effort by making significant positive changes in behavior and reflex reactions to stress and other things that prompted past drug use, not by simply taking medication. Gaining experience with these new behavioral patterns slowly creates new brain (neural) pathways while allowing the old destructive ones to fade. Counseling, therapy, sincere self-examination and support all help to guide the patients to make the behavioral changes. The medication suppresses symptoms of cravings and withdrawal that otherwise interfere with this effort, but it’s the deliberate self-reconditioning process which is the actual recovery. Once significant experience is gained with the new patterns of behavior, the patient may be ready to transition to the medication-free phase of treatment and potentially, a path of recovery.

How does Naltrexone work against opiates in the brain?

…the psychological experience of cravings is rooted in altered brain biology…”

Opioids attach to receptors in the brain, with three main effects; reduced respiration, euphoria, decreased pain. The more opioids ingested the more of an effect. The process of opioids binding to the receptors can be thought of as a mechanical union, the better the fit the more the opioid effect. Naltrexone acts like an opioid but with a different result. It too binds to the receptors, however, without a perfect fit. As a result the Naltrexone blocks the receptors preventing the opioid effects; and the Naltrexone implant tends to stay with the receptors, blocking them for up to 6 months or more.

Researching Naltrexone

Researching Naltrexone and External Links

​Following is a sample in the growing body of research available on Naltrexone and it is recommended you conduct a through investigation to determine if Naltrexone can be of help to you or the one you love. We will continue to add to this list as relevant, reliable and accurate information emerges. Please feel free to contact us at any time, and we’ll do our best to get you answers.

Implant Clinical Trial Study Results:
Implant Study results